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Transamerica is a 2005 independent comedy-drama.The film tells the story of Bree, a transsexual woman (Felicity Huffman), who goes on a road trip with her long-lost son Toby (Kevin Zegers).

The film is marked by an Academy Award--nominated and Golden Globe--winning performance by Huffman, who is also known for her performance in Desperate Housewives.

One of the major themes of the film is the personal journey toward self-discovery, according to interviews with the director and actors.[citation needed] The screenplay was inspired in part by conversations between screenwriter/director Duncan Tucker and his then roommate Katherine Connella.

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